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Case Reports
. 1980 Jan;12(1):47-51.
doi: 10.1111/j.1365-2265.1980.tb03131.x.

Size reduction of a prolactin secreting adenoma during long-term treatment with the dopamine agonist lisuride

P G Chiodini, A Liuzzi, G Verde, R Cozzi, F Silvestrini, M T Marsili, R Horowski, F Passerini, G Luccarelli, P G Borghi
Case Reports

Size reduction of a prolactin secreting adenoma during long-term treatment with the dopamine agonist lisuride

P G Chiodini et al. Clin Endocrinol (Oxf). 1980 Jan.

Abstract

A 38-year-old amenorrhoeic woman suffering from a prolactin (PRL) secreting adenoma, which had suprasellar extension as shown by caroe agonist (lisuride). PRL levels were lowered and after 1 year of treatment CAT showed a marked reduction of the tumour size. After 2 years of treatment menstruation returned and CAT demonstrated a further reduction of the adenomatous tissue. This study supports the suggestion that dopamine agonists possess an anti-proliferative effect on tumoural lactotrophic cells of humans.

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