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. 1980 Mar-Apr;7(2):215-7.
doi: 10.1111/j.1440-1681.1980.tb00064.x.

Responsiveness of hypertensive subjects to prazosin

G S Stokes, J C Monaghan, E P MacCarthy, H F Oates

Responsiveness of hypertensive subjects to prazosin

G S Stokes et al. Clin Exp Pharmacol Physiol. 1980 Mar-Apr.

Abstract

1. Plasma drug levels and blood pressure changes produced by a single 2 mg oral dose of prazosin were determined in nine hypertensive patients. 2. Regression analysis showed that there was a high degree of correlation between plasma prazosin concentration and change in mean blood pressure. 3. There were marked differences between patients in their responsiveness to prazosin.

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