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Comparative Study
. 1980 Apr 15;36(4):377-9.
doi: 10.1007/BF01975096.

Structure and toxicity of the alkaloids of Russian comfrey (symphytum x uplandicum Nyman), a medicinal herb and item of human diet

C C Culvenor, M Clarke, J A Edgar, J L Frahn, M V Jago, J E Peterson, L W Smith
Comparative Study

Structure and toxicity of the alkaloids of Russian comfrey (symphytum x uplandicum Nyman), a medicinal herb and item of human diet

C C Culvenor et al. Experientia. .

Abstract

Eight pyrrolizidine alkaloids of hepatotoxic type have been indentified in leaves of Symphytum X uplandicum. The combined alkaloids exhibit chronic hepatotoxicity in rats.

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