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. 1980 Apr 15;36(4):429-30.
doi: 10.1007/BF01975129.

The effect of caerulein on epithelial growth in the mouse gall bladder

P Putz, L Bazira, G Willems

The effect of caerulein on epithelial growth in the mouse gall bladder

P Putz et al. Experientia. .

Abstract

Caerulein, a synthetic decapeptide, was injected into mice in order to study its effect on DNA-synthesis activity in the gall bladder epithelium. Histoautoradiography after the injection of labeled thymidine was used. Higher labeling indices were observed at 8, 12, 12 and 24 h after caerulein injection. These data indicate that caerulein, apart from its cholecystokinetic effects, exerts a trophic effect on the gall bladder mucosa.

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