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. 1980 Jan;3(1):45-50.

The effect of aging on complement activity (CH50) and complement protein levels

  • PMID: 7381926

The effect of aging on complement activity (CH50) and complement protein levels

K Nagaki et al. J Clin Lab Immunol. 1980 Jan.

Abstract

Total complement activity (CH50), and the protein levels of C1q, C4, C3, C5, C9, factor B and C1 inactivator were measured in the 1,130 sera obtained from healthy subjects aged between 20 and 79 years old. Increase in the levels of CH50, C1q, C4, C3, C5 and C9 and decrease of factor B were found in the older age group. The level of C1 inactivator showed little variation with aging.

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