Case Reports
Acute splenic sequestration in hemoglobin sickle O-Arab disease
- PMID: 7382253
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Case Reports
Acute splenic sequestration in hemoglobin sickle O-Arab disease
Johns Hopkins Med J.
1980 Jun.
Abstract
A white girl with sickle O-Arab disease (Hb S/O-Arab) had three separate episodes of acute splenic sequestration at 8, 12, and 15 months of age with hemoglobin levels falling to 3.9, 2.8, and 4.2 g/dl, respectively. Functional hyposplenism was suggested by the radionucleotide spleen scan. Following splenectomy her hemoglobin stabilized in the range of 0.7--8.5 g/dl. Life-threatening episodes of splenic sequestration, pneumococcal infections and osteomyelitis may occur in both Hb S/O-Arab and homozygous sickle cell diseases.
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