doi: 10.1007/BF01981410.
Age-dependent response of lactate dehydrogenase of pituitary of rat to testosterone
- PMID: 738392
- DOI: 10.1007/BF01981410
Item in Clipboard
Age-dependent response of lactate dehydrogenase of pituitary of rat to testosterone
Experientia.
.
Abstract
The effects of time and various doses of testosterone on the responsiveness of lactate dehydrogenase of pituitary of 7-, 38- and 78-week-old rats were studied. The activity of the enzyme increases in 78-week-old rats. Castration decreases the enzyme activity at all ages. Maximum increase in the enzyme activity is seen with 50 and 100 microgram of testosterone 4 h after administration of hormone to castrated rats. No further time and dose-dependent effect is observed. The magnitude of increase for the enzyme is higher at the age of 38 weeks and decreases in 78-week-old rats.
Similar articles
-
Correlation between sexual steroid effect and activity changes and isoenzyme distribution of lactate dehydrogenase (EC 1.1.1.27) in rat anterior pituitary.Endokrinologie. 1976 Jul;67(3):257-66. Endokrinologie. 1976. PMID: 976199
-
The antigonadotropic action of testosterone but not 7alpha-methyl-19-nortestosterone is attenuated through the 5alpha-reductase pathway in the castrated male rat pituitary gland.J Androl. 2000 Mar-Apr;21(2):268-75. J Androl. 2000. PMID: 10714822
-
Effect of gonadal hormones on enzyme activities in brain and pituitary of male and female rats.Brain Res. 1975 Mar 21;86(2):283-92. doi: 10.1016/0006-8993(75)90703-9. Brain Res. 1975. PMID: 1115998
-
Effect of hormonal steroids on lactate dehydrogenase activity and its isozymes in the coagulating gland of castrated male rats.Int J Androl. 1981 Oct;4(5):582-9. doi: 10.1111/j.1365-2605.1981.tb00740.x. Int J Androl. 1981. PMID: 7319645
-
Study of lactate dehydrogenase (EC 1.1.1.27) activity and isoenzyme distribution in rat anterior pituitary, neurohypophysis, hypothalamus and in the pineal gland.Endokrinologie. 1976 Jul;67(3):267-76. Endokrinologie. 1976. PMID: 976200 No abstract available.