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. 1976 Aug 21;2(7982):389-91.
doi: 10.1016/s0140-6736(76)92406-5.

Stimulation of lymphocytes from patients with coeliac disease by a subfraction of gluten

Stimulation of lymphocytes from patients with coeliac disease by a subfraction of gluten

K Sikora et al. Lancet. .

Abstract

Peripheral-blood lymphocytes from patients with coeliac disease showed a marked increase in D.N.A. synthesis after incubation in vitro with a subfraction of gluten. Lymphocytes from control patients showed no increased D.N.A. synthesis under the same conditions. The possible use of this specific lymphocyte-stimulation assay as a screening test for coeliac disease is discussed.

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