[Dynamics of incorporation of 3H-actinomycin D into synchronized Chinese hamster cells]
[Article in
Russian]
- PMID: 7385369
Item in Clipboard
[Dynamics of incorporation of 3H-actinomycin D into synchronized Chinese hamster cells]
[Article in
Russian]
Tsitologiia.
1980 Feb.
Abstract
Dynamics of 3H-actinomycin D (3H-AMD) incorporation has been studied in the Chinese hamster synchronized cell culture (line 237) during different cell cycle phases. Intensive isotope inclusions were seen in cells during interphase: in the beginning of G1 period, in the early S period, and in the late S period, during the cell passage to G2 stage. The authors suggest that the binding of 3H-AMD by cells may be due not only to conformational changes of DNA structure, but also due to the variation in cell membrane penetration throughout the mitotic cycle.
Similar articles
-
Changes in DNA capacity for actinomycin-D binding in nuclei of interphase cells.Gen Physiol Biophys. 1985 Dec;4(6):631-9. Gen Physiol Biophys. 1985. PMID: 3841326
-
[Effect of the inhibition of a synthesis processes in the S-period on the subsequent course of mitosis in a synchronized Chinese hamster cell culture].Biull Eksp Biol Med. 1979 Mar;87(3):283-6. Biull Eksp Biol Med. 1979. PMID: 427282 Russian.
-
Rates of incorporation of radioactive molecules during the cell cycle.J Cell Physiol. 1981 Aug;108(2):135-44. doi: 10.1002/jcp.1041080204. J Cell Physiol. 1981. PMID: 7196407
-
[Inhibition by actinomycin D of ribosomal RNA synthesis in the presynthesis period of the mitotic cycle of Chinese hamster cell cultures].Tsitologiia. 1975 Jul;17(7):797-802. Tsitologiia. 1975. PMID: 1172311 Russian.
-
[Electron-radioautographic analysis of 3H-thymidine distribution in the cell nuclei of the Chinese hamster].Tsitologiia. 1983 Sep;25(9):1013-8. Tsitologiia. 1983. PMID: 6359600 Review. Russian.