Case Reports
doi: 10.1007/BF00286966.
Isochromosome 17q in two cases of acute blast transformation in myeloproliferative disorders
- PMID: 738722
- DOI: 10.1007/BF00286966
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Case Reports
Isochromosome 17q in two cases of acute blast transformation in myeloproliferative disorders
Hum Genet.
.
Abstract
Two cases of acute blast cell transformation in myeloproliferative disorders associated with a dicentric 17q isochromosome are reported. In both cases, the karyotypes also included a Philadelphia 9q;22q translocation, and in one case, an additional chromosome 8 (trisomy 8).
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