doi: 10.1007/BF01318021.
Gene constellation of live influenza A vaccines
- PMID: 7387405
- DOI: 10.1007/BF01318021
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Gene constellation of live influenza A vaccines
Arch Virol.
1980.
Abstract
The genotypic composition of several H3N2 vaccinal strains made from PR/8/34 and different wild isolates has been determined. The results suggested that specific gene constellations at the level of the 3 largest RNA fragments, coding the 3 "polymerase proteins" are responsible for their consistent attenuation.
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