Kinetics of suicide substrates
- PMID: 7387634
- PMCID: PMC1161457
- DOI: 10.1042/bj1850771
Kinetics of suicide substrates
Abstract
When suicide substrates inactivate enzymes during catalysis, formation of product and inactivation of enzyme proceed concurrently. The steady-state hypothesis is applicable when catalytic quantities of enzyme are used. Equations for the rate of inactivation have been derived and integrated to obtain equations describing progress curves.
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