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. 1980 Feb;102(2):179-84.
doi: 10.1111/j.1365-2133.1980.tb05690.x.

Psoriasis and HLA-Cw6

A Tiilikainen, A Lassus, J Karvonen, P Vartiainen, M Julin

Psoriasis and HLA-Cw6

A Tiilikainen et al. Br J Dermatol. 1980 Feb.

Abstract

The prevalence of histocompatibility antigen HLA-Cw6 was 72.7% in twenty-two patients with the guttate form and 45.9% in thirty-seven patients with the vulgaris form of psoriasis; the difference between these figures and the prevalence (7.4%) in 462 healthy blood donors in Finland is highly significant. The previously observed excess of several HLA-B locus genes might be secondary to their close linkage with the Cw6 gene. Hereditary factors appear more important in the guttate than in the vulgaris form of psoriasis.

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