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. 1980 Jul 3;286(5768):25-8.
doi: 10.1038/286025a0.

Nerve growth factors in the rat iris

Nerve growth factors in the rat iris

T Ebendal et al. Nature. .

Abstract

Nerve growth factor (NGF) activity was not detected by bioassay in irides killed immediately after excision but NGF appeared within 24 h in living irides placed in culture or grafted to a host eye. Furthermore, sensory and, although less effective, sympathetic denervation of irides in situ led within 10 days to the appearance of NGF activity. In addition, freezing and thawing released a parasympathetic neuronotrophic factor activity from irides.

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