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Comparative Study
. 1978 Oct;21(4):219-22.

A clinical trial of indomethacin and ibuprofen in dysmenorrhea

D R Halbert, L M Demers
  • PMID: 739472
Comparative Study

A clinical trial of indomethacin and ibuprofen in dysmenorrhea

D R Halbert et al. J Reprod Med. 1978 Oct.

Abstract

Forty patients with primary dysmenorrhea were treated with antiprostaglandin agents. Seventeen were treated with indomethacin, with 71% obtaining significant relief. Of 23 treated with ibuprofen, 87% obtained significant relief. Nausea occurred in 49%, vomiting in 23% and stool frequency in 35%. All of these gastro-intestinal symptoms were relieved by both drugs. Ibuprofen was free of side effects, but four patients had headaches or peculiar psychic effects on indomethacin.

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