doi: 10.1016/0304-4165(80)90295-0.
Platelet factor 4 regulates osteoclastic bone resorption in vitro
- PMID: 7397235
- DOI: 10.1016/0304-4165(80)90295-0
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Platelet factor 4 regulates osteoclastic bone resorption in vitro
Biochim Biophys Acta.
.
Abstract
Platelet factor 4, which inhibits collagenases derived from both human skin and granulocytic extracts, was found to block reversibly parathyroid hormone-stimulated 45Ca release from fetal rat bone in vitro. The inhibitory property was equally effective in both actively resorbing bones and in bones stimulated to initiate resorption.
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