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. 1980 May;4(5):459-69.
doi: 10.1016/0309-1651(80)90033-8.

Nonrandom chromosome changes in nine rat liver epithelial cell lines

M F Exilie, C Turc, M Chessebeuf, P Padieu

Nonrandom chromosome changes in nine rat liver epithelial cell lines

M F Exilie et al. Cell Biol Int Rep. 1980 May.

Abstract

Using G-banding technique, the karyotypes of nine liver epithelial cell lines from Wistar rats cultivated under standard conditions were studied in early successive passages. Preferential involvement of chromosome n 1 abnormalities including numerical and structural changes appeared at about the 14th passage. These apparently nonrandom chromosome changes have been compared with those found in neoplastic cell lines.

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