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. 1980 Jul 11;65(1):113-7.
doi: 10.1016/0014-2999(80)90219-8.

Effects of electrical stimulation on the enkephalins in guinea-pig small intestine

Effects of electrical stimulation on the enkephalins in guinea-pig small intestine

A D Corbett et al. Eur J Pharmacol. .

Abstract

When myenteric plexus-longitudinal muscle preparations of the guinea-pig small intestine are stimulated electrically in the presence of cycloheximide there is a decrease in the content of enkephalins which is taken to be due to their release. With supramaximal stimuli, the release per pulse is similar at 1 and 10 Hz but it is lower with submaximal than with maximal stimuli. Met-enkephalin is more readily released than Leu-enkephalin.

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