Prostaglandins and gastric ulcer
- PMID: 7399494
- DOI: 10.1080/21548331.1980.11946630
Prostaglandins and gastric ulcer
Abstract
Interest in the prostaglandins as possible gastric-mucosal cytoprotective agents was first aroused by the oberved antagonism between these compounds and ulcerogenic anti-inflammatory drugs. It has now been shown that several PGs can depress gastric acid secretion and reduce HCl-induced lesions in experimental animals. The clinical implications appear to be well worth exploration.