[Characteristics of the formation of substances by various microorganisms that stimulate levorin biosynthesis]

Abstract

Production specific properties of substances stimulating levorin biosynthesis by various microorganisms were studied. It was noted that substances activating the biosynthesis of levorin were produced by various species of yeast-like fungi. Filtrates of the fermentation broths of bacteria, yeasts or filamentous fungi did not contain substances increasing the antibiotic synthesis. Filtrates of the fermentation broth of yeast-like fungi increased also the synthesis of polyenic antibiotics, such as mycoheptin and amphotericin and suppressed production of nystatin.