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. 1980 Sep 1;631(3):507-10.
doi: 10.1016/0304-4165(80)90028-8.

Rapid mobilization of ferritin iron by ascorbate in the presence of oxygen

H F Bienfait, M L van den Briel

Rapid mobilization of ferritin iron by ascorbate in the presence of oxygen

H F Bienfait et al. Biochim Biophys Acta. .

Abstract

L-(-)-ascorbate mobilizes iron from horse-spleen ferritin in the presence of oxygen at pH 8.0. The reaction is strongly stimulated by Cu2+. Dehydroascorbate and other stable oxidation products of ascorbate are ineffective. We present evidence that monodehydroascorbate mobilizes ferritin iron by reduction.

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