doi: 10.1016/0378-3782(80)90019-5.
Mucosal receptor for IgA in the breast-fed neonate
- PMID: 7408746
- DOI: 10.1016/0378-3782(80)90019-5
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Mucosal receptor for IgA in the breast-fed neonate
Early Hum Dev.
1980 Jun.
Abstract
Immunoglobulin A from human milk binds to neonatal buccal cells. Pretreatment of the cells with anti-secretory component antiserum blocks this binding, suggesting that secretory component (SC) contributes to the adhesive process. The concentrations of SC in saliva of preterm neonates is lower than that of full-term infants. This may lower the effectiveness of mucosal immunity passively transferred from the mother.
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