Myogenic receptivity for Met-enkephalin in the rat duodenum: comparison with the guinea-pig duodenum
- PMID: 7408961
- DOI: 10.1016/0014-2999(80)90305-2
Myogenic receptivity for Met-enkephalin in the rat duodenum: comparison with the guinea-pig duodenum
Abstract
Met-enkephalin (ENK) induced a dose-dependent transient relaxation in vitro in the rat duodenum while morphine neither induced a response nor affected the response to ENK. The response was not blocked by tetrodotoxin but was abolished by naloxone. The response of guinea-pig duodenum to ENK was either relaxation or pulsatile contractions depending on the dose and was abolished by tetrodotoxin.
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