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Comparative Study
. 1980 Aug 22;66(1):129-32.
doi: 10.1016/0014-2999(80)90305-2.

Myogenic receptivity for Met-enkephalin in the rat duodenum: comparison with the guinea-pig duodenum

K Furukawa, T Nomoto, T Tonoue
Comparative Study

Myogenic receptivity for Met-enkephalin in the rat duodenum: comparison with the guinea-pig duodenum

K Furukawa et al. Eur J Pharmacol. .

Abstract

Met-enkephalin (ENK) induced a dose-dependent transient relaxation in vitro in the rat duodenum while morphine neither induced a response nor affected the response to ENK. The response was not blocked by tetrodotoxin but was abolished by naloxone. The response of guinea-pig duodenum to ENK was either relaxation or pulsatile contractions depending on the dose and was abolished by tetrodotoxin.

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