Binding of non-mammalian immunoglobulins to staphylococcal protein A
- PMID: 7409269
Binding of non-mammalian immunoglobulins to staphylococcal protein A
Abstract
Immunoglobulins M of the chicken (about 3% of serum IgM), clawed toad (12%) and carp (13%) bind to the protein A-Sepharose. A monomeric immunoglobulin with four domain heavy chains from the chicken serum is also bound (30% of bound immunoglobulins). The protein A-Sepharose can be utilized for isolation of IgM of the clawed toad and carp directly from the serum.
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