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. 1980 Jul 26;2(SP1):12-4.

Prediction of response to antihypertensive therapy with prazosin

E P MacCarthy, G W Frost, J C Monaghan, B A Mennie, G S Stokes
  • PMID: 7421719

Prediction of response to antihypertensive therapy with prazosin

E P MacCarthy et al. Med J Aust. .

Abstract

Blood-pressure responses and changes in plasma drug concentration were studied in 11 hypertensive patients after an initial oral dose of 2 mg of prazosin. Subsequently, blood pressure was monitored during long-term treatment with prazosin. The prazosin reactivity index, a value derived during the first-dose study, appeared to predict the long-term antihypertensive effect of prazosin alone or prazosin combined with bendrofluazide.

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