Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1980;26(9):45-8.

[Nucleotide composition and the methylated cytosine level in the DNA from a cancerous stomach tumor]

[Article in Russian]
R I Kliasheva, V E Volkov, G A Panfilova
  • PMID: 7423903
Comparative Study

[Nucleotide composition and the methylated cytosine level in the DNA from a cancerous stomach tumor]

[Article in Russian]
R I Kliasheva et al. Vopr Onkol. 1980.

Abstract

Under study was the nucleotide content and the level of methylated cytosine (5-MC) in the DNA, isolated from adenocarcinoma of the stomach, gastric mucosa in patients with duodenal ulcer as well as from the mucosa of intact human stomach. The difference (reliable statistically) was found in the amount of 5-MC between the tissues concerned. So, in adenocarcinoma the amount of 5-MC was 4.64 +/- 0.3 mol.%, in gastric mucosa in case of duodenal ulcer--2.63 +/- 0.3 mol.%, while in mucosa of intact stomach--1.52 +/- 0.3 mol.%. The increased level of DNA methylation should influence its structure and activity.

PubMed Disclaimer

LinkOut - more resources