[Study results of the comprehensive influenza prevention with vaccines and remantadine during the influenza A(H1N1) outbreak in 1979]

Abstract

During an outbreak of influenza in April, 1979, caused by A (H1N1) virus the protective effect of remantadine in combination with vaccinations using a national-made live A (H3N2) and inactivated A (H1N1) and B vaccines was studied. The best protective effect was achieved in the subjects vaccinated with influenza vaccines and given remantadine for urgent prophylaxis. Vaccination prophylaxis reduced the incidence of influenza and ARD 1.4-fold, prophylaxis with remantadine alone 2.3-fold.