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. 1977;55(3):225-31.
doi: 10.1007/BF01319908.

Enhancement of antiviral protection against encephalomyocarditis virus by a combination of isoprinosine and interferon

C Chany, I Cerutti

Enhancement of antiviral protection against encephalomyocarditis virus by a combination of isoprinosine and interferon

C Chany et al. Arch Virol. 1977.

Abstract

The antiviral effect of interferon against encephalomyocarditis (EMC) virus infection in mice was enhanced by isoprinosine. However, the enhancement was only obtained when both interferon and the virus were inoculated into the peritoneum; the inoculation route of isoprinosone did not modify significantly the final results. In addition, the time sequence of injections was of great importance; generally the injection of isoprinosine had to precede that of interferon by a few hours.

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