Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1980 Sep;32(5):754-60.

Detection of inbreeding effects by the chi-square test on genotypic and phenotypic frequencies

M Haber

Detection of inbreeding effects by the chi-square test on genotypic and phenotypic frequencies

M Haber. Am J Hum Genet. 1980 Sep.

Abstract

The problem of detection of inbreeding effects by the chi-square goodness-of-fit test is investigated. The noncentrality parameter of the limiting chi-square distribution is considered as a function of the inbreeding coefficient in two models: (1) a gene locus with m codominant alleles and (2) the generalized ABO model. Previous results by Ward and Sing and by Chakraborty and Rao were based on inadequate statistical reasoning. In the first model, the resulting noncentrality parameter is identical with that found by Ward and Sing. For the second model, the limiting noncentrality parameter is found to be zero.

PubMed Disclaimer

References

    1. Am J Hum Genet. 1971 Jan;23(1):97-8 - PubMed
    1. Ann Hum Genet. 1968 May;31(4):409-20 - PubMed
    1. Am J Hum Genet. 1970 Jan;22(1):112-3 - PubMed
    1. Biometrics. 1968 Dec;24(4):915-35 - PubMed
    1. Am J Hum Genet. 1974 Jul;26(4):444-53 - PubMed

Substances

LinkOut - more resources