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. 1980 Oct 11;281(6246):973-4.
doi: 10.1136/bmj.281.6246.973.

Effect of treatment of hyperlipidaemia on haemostatic variables

R S Elkeles, R Chakrabarti, M Vickers, Y Stirling, T W Meade

Effect of treatment of hyperlipidaemia on haemostatic variables

R S Elkeles et al. Br Med J. .

Abstract

The haemostatic function of 11 men with hyperlipidaemia was measured before and after they were treated with a carbohydrate-reduced, fat-modified diet. After treatment, which significantly reduced serum triglyceride and cholesterol concentrations, they showed a significant fall in mean levels of clotting factors VII, VIII, and X and a rise in fibrinolytic activity. These findings suggest that haemostatic function may be important in the pathogenesis of ischaemic heart disease.

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