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Case Reports
. 1980 Jul;4(4):413-28.
doi: 10.1111/j.1365-2559.1980.tb02936.x.

Lobular endocrine neoplasia in fibroadenoma of the breast

V Eusebi, J G Azzopardi
Case Reports

Lobular endocrine neoplasia in fibroadenoma of the breast

V Eusebi et al. Histopathology. 1980 Jul.

Abstract

Four cases of endocrine neoplasia within fibroadenomas of the breast are described. The tumours are identifiable by light microscopic, silver impregnation and ultrastructural studies. Argyrophilia and the presence of dense-core granules establish the identity of this tumour type. The differential diagnosis from, and possible relation to, lobular carcinoma in situ are discussed.

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