Expression of the teratocarcinoma phenotype in hybrids between totipotent mouse teratocarcinoma and myeloma cells
- PMID: 7430268
- DOI: 10.1002/jcp.1041050110
Expression of the teratocarcinoma phenotype in hybrids between totipotent mouse teratocarcinoma and myeloma cells
Abstract
We have produced somatic cell hybrids between totipotent mouse teratocarcinoma and myeloma cells. These hybrids behave like the teratocarcinoma cell parent and express teratocarcinoma embryonal antigens. However, they also express the myeloma H-2 antigens. THe availability of these hybrids should make it possible to study the expression of already rearranged immunoglobulin genes during mouse development.
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