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Case Reports
. 1980 Aug;33(8):730-4.
doi: 10.1136/jcp.33.8.730.

Marrow hypoplasia with splenomegaly in adolescence

J H Robertson, P Burnside, D C Salmon
Case Reports

Marrow hypoplasia with splenomegaly in adolescence

J H Robertson et al. J Clin Pathol. 1980 Aug.

Abstract

Four adolescents presented with leucopenia, thrombocytopenia, and splenomegaly; three had associated congenital abnormalities and two had a cirrhosis. They provide further evidence of an association between hepatic disease and bone marrow dysfunction. It is considered that these patients suffer from a genetic or constitutional disorder which may result in a susceptibility of their bone marrow to hypoplasia following viral hepatitis or other infections.

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References

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