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. 1980 Jun;94(6):617-27.
doi: 10.1017/s0022215100089325.

Human respiratory nasal mucosa in progressive systemic sclerosis (scleroderma). An electron microscopic study

A M Talaat, M N Kamel, M T Aziz, N A Shaaban

Human respiratory nasal mucosa in progressive systemic sclerosis (scleroderma). An electron microscopic study

A M Talaat et al. J Laryngol Otol. 1980 Jun.

Abstract

The fine structure of the respiratory nasal mucosa in cases of systemic scleroderma was studied in 5 patients. The cilia were absent in all the sections examined, and the epithelium showed characteristic morphological details. Absence of the mucous elements in the sero-mucinous glands was noticed with evidence of increased activity of the serous units. The capillaries and small arterioles showed severe changes. Electron-dense deposits were seen within the various constituents of the nasal mucosa. It was assumed that the characteristics of the disease are dependent on individual reactivity of a genetically determined immune system stimulated by an undetermined factor.

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