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. 1978 Dec;38(6):745-8.
doi: 10.1038/bjc.1978.282.

Relationship between oestrogen-receptor content and histological grade in human primary breast tumours

P V Maynard, C J Davies, R W Blamey, C W Elston, J Johnson, K Griffiths
Free PMC article

Relationship between oestrogen-receptor content and histological grade in human primary breast tumours

P V Maynard et al. Br J Cancer. 1978 Dec.
Free PMC article

Abstract

A series of 300 patients presenting consecutively with primary operable breast cancer has been studied. A significant correlation was found between oestrogen-receptor (ER) content and histological grade: the better-differentiated tumours rarely lacked receptor. This correlation was significant only in women defined as post-menopausal. Data on early recurrence of disease indicate a worse prognosis for women in whom primary tumours are ER-.

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