[Quantitative determination of regional cerebral blood flow using a gamma camera]

Abstract

A method of determining the regional cerebral blood flow with the use of gamma-chamber is described, and the results of using this method for examining the changes of the flow in two patients with cerebral hemorrhage of various intervals after surgical elimination of hematoma are presented. The mean regional cerebral flow in a whole hemisphere, and the regional cerebral flow in 10 zones with projections to particular anatomic structures are determined. The isotope clearance curves were processed on a PDP/8E mini-computer. The magnitudes of the cerebral blood flow were calculated by the stochastic two-component and the initial inclination methods. The cerebral flow examinations revealed substantial changes in the patients' cerebral hemodynamics. The results obtained may be of importance for developing pathogeneticaly substantiated therapy of patients who have a cerebral stroke.