doi: 10.1007/BF00775410.
R-loop hybridization of collagen DNA: separation in Cs2SO4 gradients
- PMID: 7442662
- DOI: 10.1007/BF00775410
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R-loop hybridization of collagen DNA: separation in Cs2SO4 gradients
Mol Biol Rep.
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Abstract
High molecular weight poly(A)RNA (26-35 S) from chicken embryo trunks which is enriched for collagen mRNA was iodinated and hybridized to DNA under conditions of R-loop formation. The R-loops were separated in Cs2SO4 gradients from the bulk of DNA yielding double stranded DNA enriched for collagen genes.
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