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. 1980 Jun 11;8(11):2527-35.
doi: 10.1093/nar/8.11.2527.

A new conformation-specific infrared band of A-DNA in films

W Pohle, H Fritzsche
Free PMC article

A new conformation-specific infrared band of A-DNA in films

W Pohle et al. Nucleic Acids Res. .
Free PMC article

Abstract

A band at 1185 cm-1 occurs in the infrared spectra of nucleic acids in their A-type conformation which has been reproduced in the literature, too. The absorbance of this band is proportional to the fraction of the A form of DNA samples containing a mixture of different forms. The 1185 cm-1 band has been assigned tentatively to a vibration of the sugar-phosphate backbone with a fairly high contribution from the sugar moiety. Drastic dehydration of the DNA films is accompanied by a continuous intensity decrease of the 1185 cm-1 band indicating a collapse of the A form.

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