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Case Reports
. 1980 May;56(655):356-8.
doi: 10.1136/pgmj.56.655.356.

Amiodarone-induced thyrotoxicosis: four cases and a review of the literature

S Keidar, E Grenadier, A Palant
Case Reports

Amiodarone-induced thyrotoxicosis: four cases and a review of the literature

S Keidar et al. Postgrad Med J. 1980 May.

Abstract

Hyperthyroidism is a rare side effect of amiodarone treatment. Four patients with this untoward effect are described One patient with mild hyperthyroidism before treatment with amiodarone, developed prolonged severe resistant thyrotoxicosis 6 months after initiation of this drug. A second patient with Wolf-Parkinson-White syndrome and paroxysmal atrial fibrillation was successfully stabilized with amiodarone for 18 months. However, the arrhythmia recurred and the thyroid function tests were found to be elevated. In 2 other patients only slight elevation of the thyroid function tests were found without clinical manifestations 4 months after treatment with amiodarone had been initiated.

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