Phosphorus distribution in the nucleosome
- PMID: 7444457
- DOI: 10.1126/science.7444457
Phosphorus distribution in the nucleosome
Abstract
The spatial distribution of phosphorus within active fraction nucleosomes reveals that the path of the DNA is consistent with one and three-fourths turns of DNA supercoiled around the outside of the protein core. This phosphorus distribution, obtained with an imaging electron spectrometer in a conventional transmission electron microscope, simultaneously establishes new limits of sensitivity for elemental microanalysis.
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