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. 1980 Dec;90(6):783-91.
doi: 10.1016/s0002-9394(14)75193-1.

Lipofuscin of human retinal pigment epithelium

L Feeney-Burns, E R Berman, H Rothman

Lipofuscin of human retinal pigment epithelium

L Feeney-Burns et al. Am J Ophthalmol. 1980 Dec.

Abstract

Analysis of the fluorescent spectra of chloroform-methanol extracts of human retinal pigment epithelium confirmed the presence of lipofuscin pigments in the pigment epithelium of older individuals. Similar fractions in the pigment epithelium of young individuals were present in insufficient quantities for spectral analysis. Electron microscopy of the pigment epithelium of these eyes showed few or no lipofuscin granules in young eyes but large numbers in older eyes.

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