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. 1980;66(3):275-82.
doi: 10.1007/BF01314742.

Rimantadine hydrochloride blocks the second step of influenza virus uncoating

A G Bukrinskaya, N K Vorkunova, R A Narmanbetova

Rimantadine hydrochloride blocks the second step of influenza virus uncoating

A G Bukrinskaya et al. Arch Virol. 1980.

Abstract

Two steps of influenza virus A/WSN uncoating in MDCK cells are described. The products of the first step are cores which accumulate in the nuclear-associated cytoplasm. The products of the second step are ribonucleoproteins which penetrate the nuclei. Rimantadine blocks the second step without interfering with the first one.

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