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. 1981 Jan;65(1):63-6.
doi: 10.1136/bjo.65.1.63.

Antibodies to lens antigens in cataract and after cataract surgery

S H Nissen, P Andersen, H M Andersen

Antibodies to lens antigens in cataract and after cataract surgery

S H Nissen et al. Br J Ophthalmol. 1981 Jan.

Abstract

By means of an enzyme-linked immunosorbent assay (ELISA) antibodies to whole lens homogenate were found in 50.0% of 38 patients with senile cataract and in 57.3% of 75 controls. The antibody titres were in the range of 10-160 in both groups. IgG antibodies occurred in 44.7% of patients and in 45.3% of controls, whereas IgM antibodies were found in 21.1% of the patients and in 40.0% of the controls (not significant). Postoperative uveitis occurred in 5 (31.6%) of 19 patients, who had antibodies in serum prior to the operation and in only 2 (10.5%) of 19 antibody-negative patients (P = 0.10).

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