[Experimental study of the allergenic activity of the pollen of Cyclachena xanthifolia]

Abstract

Comparative studies of Cyclachena xantifolia and Ambrosia artemisifolia have been carried out by light, scanning and electron microscopy. Cyclachena xantifolia allergic properties have been examined in guinea-pigs. Senstization of animals has caused the increased number of immunocompetent cells in regional and distant lymph nodes, the appearance of high titers of reagin-like antibodies capable of fixing in the skin. Injection of the proper dose of allergen has resulted in the development of anaphylactic shock of different severity. The role of Cyclachena xantifolia in the etiology of pollinoses has been ascertained.