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. 1980 Nov 15;36(11):1294-5.
doi: 10.1007/BF01969596.

In situ aging of auricular chondrocytes is not due to the exhaustion of their replicative potential

S Moskalewski, A Gołaszewska, T Ksiazek

In situ aging of auricular chondrocytes is not due to the exhaustion of their replicative potential

S Moskalewski et al. Experientia. .

Abstract

Multiplication of chondrocytes during growth of rabbit auricular cartilage was estimated on the basis of total DNA determination and compared with the population doubling level reached by these chondrocytes in vitro. The results indicate that the in situ aging of auricular chondrocytes is caused by factors other than the intrinsic depletion of their growth potential.

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