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. 1980 Nov;19(5):465-7.
doi: 10.1007/BF00281827.

Heterogeneity of the haemoglobin-A1c-band in isoelectric focussing

B S Welinder, P A Svendsen

Heterogeneity of the haemoglobin-A1c-band in isoelectric focussing

B S Welinder et al. Diabetologia. 1980 Nov.

Abstract

A double HbA1c-band was demonstrated in isoelectric focussing of blood from diabetics with a fasting blood glucose above 11 mmol/l. The same band-doubling was also demonstrated after incubation of erythrocytes in glucose/saline solutions. This finding may reflect the presence of the initial condensation product between haemoglobin and glucose, the Schiff-base intermediate.

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