The evolution of white matter disease as seen on computed tomography
- PMID: 7455118
- DOI: 10.1148/radiology.138.2.7455118
The evolution of white matter disease as seen on computed tomography
Abstract
The evolving computed tomographic (CT) findings in three patients with different types of dysmyelinating white matter diseases (Krabbe, Canavan, ketotic hyperglycinemia) are presented. Serial CT scans suggested that the abnormal, low density white matter, which is characteristic of many white matter diseases, is present for only a limited time, corresponding to active dys- or demyelination. The low density abnormality gives way to a nonspecific final common pathway manifested as severe atrophy on CT. Ventricular enlargement is accentuated in this form of atrophy which appears to be the final stage in a wide variety, if not all, of white matter diseases.
MeSH terms
LinkOut - more resources
Full Text Sources