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. 1980 Dec;37(4):637-40.
doi: 10.1016/0021-9150(80)90071-4.

The influence of diet-induced hypercholesterolemia on the degree of oxidation of glutathione in rabbit aorta

H Heinle, H Liebich

The influence of diet-induced hypercholesterolemia on the degree of oxidation of glutathione in rabbit aorta

H Heinle et al. Atherosclerosis. 1980 Dec.

Abstract

In rabbits fed a cholesterol-rich diet for 4 weeks, an increased lipid peroxidation rate was found in plasma and aortic wall tissue. Furthermore, there was a significant increase of glutathione disulfide in aortic tissue indicating a mechanism whereby hypercholesterolemia may influence sulfhydryl group-dependent reactions of vessel wall metabolism.

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