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. 1980 Dec;11(2):169-72.
doi: 10.1016/0304-3835(80)90108-1.

Liver-cell tumours in rats fed hexachlorobenzene

A G Smith, J R Cabral

Liver-cell tumours in rats fed hexachlorobenzene

A G Smith et al. Cancer Lett. 1980 Dec.

Abstract

All animals in a group of female Agus rats fed 100 ppm of hexachlorobenzene (HCB) in their diet for up to 90 weeks developed multiple liver-cell tumours whereas none were seen in control rats. There was no evidence of skin lesions or nervous symptoms usually seen with higher doses of HCB. A high incidence of liver-cell tumours was also seen with MRC Wistar female rats fed HCB for 75 weeks.

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